CD5 抗体
Quick Overview for CD5 抗体 (ABIN6297702)
抗原
See all CD5 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse anti-Human/Rhesus Monkey. CD5 Antibody [Sodium Azide Free]
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特异性
- Cell surface
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纯化方法
- Stimulated human leukocytes were used as the immunogen for this CD5 antibody.
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免疫原
- Stimulated human leukocytes were used as the immunogen for this CD5 antibody.
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应用备注
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Functional Testing: order BSA/azide-free format
FACS: 0.5-1 μg/million cells
IF: 0.5-1 μg/mL -
限制
- 仅限研究用
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缓冲液
- In 1X PBS ( pH 7.4), BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- CD5
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别名
- T-cell surface glycoprotein CD5
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背景
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Target Description: This antibody recognizes a 67 kDa transmembrane protein, which is identified as CD5. It is found on 95 % of thymocytes and 72 % of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in Tcell areas. CD5 antibody is a pan Tcell marker that also reacts with a range of neoplastic Bcells, e.g. chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), mantle cell lymphoma, and a subset (~10 %) of diffuse large Bcell lymphoma. Aberrant expression is useful in making a diagnosis of mature Tcell neoplasms. CD5 antibody detection is diagnostic in CLL/SLL within a panel of other Bcell markers, especially one that includes anti-CD23. CD5 antibody is also very useful in differentiating among mature small lymphoid cell malignancies. In addition, it can be used in distinguishing thymic carcinoma (+) from thymoma (-). It does not react with granulocytes or monocytes.
Gene Symbol: CD5///LEU1
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基因ID
- 921
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UniProt
- P06127
抗原
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