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CD46 抗体

CD46 适用: 人, Baboon FACS, IF 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN6297689
发货至: 中国
  • 抗原 See all CD46 抗体
    CD46
    适用
    • 117
    • 39
    • 20
    • 10
    • 9
    • 1
    人, Baboon
    宿主
    • 85
    • 52
    • 2
    小鼠
    克隆类型
    • 73
    • 66
    单克隆
    标记
    • 52
    • 18
    • 16
    • 9
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD46 antibody is un-conjugated
    应用范围
    • 92
    • 79
    • 42
    • 40
    • 33
    • 19
    • 14
    • 14
    • 14
    • 10
    • 6
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (IF)
    原理
    Mouse anti-Human/Baboon CD46 Antibody [Sodium Azide Free]
    特异性
    Cell surface
    纯化方法
    Stimulated human leukocytes were used as the immunogen for the CD46 antibody.
    免疫原
    Stimulated human leukocytes were used as the immunogen for the CD46 antibody.
    Top Product
    Discover our top product CD46 Primary Antibody
  • 应用备注
    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    In 1X PBS, BSA free, sodium azide free
    储存液
    Azide free
    储存条件
    4 °C,-20 °C
    储存方法
    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原
    CD46
    别名
    Membrane cofactor protein (CD46 产品)
    别名
    AHUS2 antibody, MCP antibody, MIC10 antibody, TLX antibody, TRA2.10 antibody, Mcp antibody, CD46 antibody, CD46 molecule antibody, CD46 antigen, complement regulatory protein antibody, CD46 molecule, complement regulatory protein antibody, membrane cofactor protein-like antibody, CD46 antibody, Cd46 antibody, LOC100341359 antibody, LOC103789310 antibody
    背景

    Target Description: Recognizes a protein of 52 kDa-58 kDa, identified as CD46 (also known as membrane cofactor protein, MCP). Its epitope is located on the four immunogenic short consensus repeat (SCR) domains at N-terminus of the protein. CD46 exists as many isoforms in a variety of tissues. It is strongly expressed on salivary gland ducts and kidney ducts, moderately on lymphocytes and endothelium, and weakly on interstitial tissues and muscle cells, but not on erythrocytes. CD46 functions as a C3b/C4b-binding glycoprotein that inhibits complement activation on host cells. It also serves as a measles virus receptor, an adherence factor for group A Streptococcus pyogenes, and a cellular pilus receptor for pathogenic Neisseria.

    Gene Symbol: CD46///MCP///MIC10

    基因ID
    4179
    UniProt
    P15529
    途径
    Regulation of Actin Filament Polymerization
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