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CD46 抗体

The 小鼠 单克隆 anti-CD46 antibody is suitable to detect CD46 in samples from 人 和 Baboon. It has been validated for FACS 和 IF.
产品编号 ABIN6297689
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD46 抗体 (ABIN6297689)

抗原

See all CD46 抗体
CD46

适用

  • 141
  • 34
  • 20
  • 10
  • 10
  • 3
人, Baboon

宿主

  • 91
  • 67
  • 2
  • 2
小鼠

克隆类型

  • 93
  • 69
单克隆

标记

  • 60
  • 16
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  • 10
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  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This CD46 antibody is un-conjugated

应用范围

  • 94
  • 88
  • 49
  • 42
  • 36
  • 28
  • 18
  • 15
  • 14
  • 9
  • 8
  • 5
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  • 2
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  • 1
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Flow Cytometry (FACS), Immunofluorescence (IF)
  • 原理

    Mouse anti-Human/Baboon CD46 Antibody [Sodium Azide Free]

    特异性

    Cell surface

    纯化方法

    Stimulated human leukocytes were used as the immunogen for the CD46 antibody.

    免疫原

    Stimulated human leukocytes were used as the immunogen for the CD46 antibody.
  • 应用备注

    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    CD46

    别名

    Membrane cofactor protein

    背景

    Target Description: Recognizes a protein of 52 kDa-58 kDa, identified as CD46 (also known as membrane cofactor protein, MCP). Its epitope is located on the four immunogenic short consensus repeat (SCR) domains at N-terminus of the protein. CD46 exists as many isoforms in a variety of tissues. It is strongly expressed on salivary gland ducts and kidney ducts, moderately on lymphocytes and endothelium, and weakly on interstitial tissues and muscle cells, but not on erythrocytes. CD46 functions as a C3b/C4b-binding glycoprotein that inhibits complement activation on host cells. It also serves as a measles virus receptor, an adherence factor for group A Streptococcus pyogenes, and a cellular pilus receptor for pathogenic Neisseria.

    Gene Symbol: CD46///MCP///MIC10

    基因ID

    4179

    UniProt

    P15529

    途径

    Regulation of Actin Filament Polymerization
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