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CD37 抗体

TSPAN26 适用: 人 FACS, IF, Func 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN6297658
发货至: 中国
  • 抗原 See all CD37 (TSPAN26) 抗体
    CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))
    适用
    • 67
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    宿主
    • 38
    • 30
    小鼠
    克隆类型
    • 39
    • 26
    • 3
    单克隆
    标记
    • 33
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    • 1
    • 1
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    This CD37 antibody is un-conjugated
    应用范围
    • 43
    • 26
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    • 19
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    • 9
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    Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)
    原理
    Mouse anti-Human CD37 Antibody [Sodium Azide Free]
    特异性
    Cell surface
    纯化方法
    Spleen cells from a patient with hairy cell leukemia were used as the immunogen for the CD37 antibody.
    免疫原
    Spleen cells from a patient with hairy cell leukemia were used as the immunogen for the CD37 antibody.
    Top Product
    Discover our top product TSPAN26 Primary Antibody
  • 应用备注
    Functional Activity (Order SAF formulation)
    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 0.5-1 μg/mL
    限制
    仅限研究用
  • 缓冲液
    In 1X PBS, BSA free, sodium azide free
    储存液
    Azide free
    储存条件
    4 °C,-20 °C
    储存方法
    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原
    CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))
    别名
    Leukocyte antigen CD37 (TSPAN26 产品)
    别名
    Tspan26 antibody, GP52-40 antibody, TSPAN26 antibody, CD37 antigen antibody, CD37 molecule antibody, Cd37 antibody, CD37 antibody
    背景

    Target Description: Recognizes a protein of 33-55 kDa, identified as CD37 (Workshop V, Code CD37.7). CD37 is strongly expressed on normal and neoplastic mature (sIg+) B-lymphocytes. In B-cell ontogeny, CD37 appears after the pre-B-cell stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells.1 CD37 is also present, at low densities, on resting and activated T cells, neutrophils, monocytes, and some myelomonocytic leukemia cells. It is absent from platelets, erythrocytes. CD37 is a member of a family of tetraspan transmembrane proteins, including CD9, CD53, CD63, CD81, and CD82. It associates other tetraspan transmembrane proteins and MHC class II molecules to form a large complex at the surface of B cells and play a role in signal transduction. CD37 is a valuable and stable marker for peripheral mature B-cells and corresponding malignancies like B-cell chronic lymphocytic leukemia (B-CLL), hairy cell leukemia (HCL), and all types of B-cell non-Hodgkin'' lymphoma (B-NHL).

    Gene Symbol: CD37///TSPAN26

    基因ID
    951
    UniProt
    P11049
    途径
    Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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