CD37 抗体
Quick Overview for CD37 抗体 (ABIN6297658)
抗原
See all CD37 (TSPAN26) 抗体适用
宿主
克隆类型
标记
应用范围
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                                            原理
- Mouse anti-Human CD37 Antibody [Sodium Azide Free]
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                                            特异性
- Cell surface
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                                            纯化方法
- Spleen cells from a patient with hairy cell leukemia were used as the immunogen for the CD37 antibody.
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                                            免疫原
- Spleen cells from a patient with hairy cell leukemia were used as the immunogen for the CD37 antibody.
 
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                                            应用备注
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                        Functional Activity (Order SAF formulation)
 Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
 Immunofluorescence: 0.5-1 μg/mL
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                                            限制
- 仅限研究用
 
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                                            缓冲液
- In 1X PBS, BSA free, sodium azide free
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                                            储存液
- Azide free
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                                            储存条件
- 4 °C,-20 °C
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                                            储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
 
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    - CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))
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                                            别名
- Leukocyte antigen CD37
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                                            背景
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                        Target Description: Recognizes a protein of 33-55 kDa, identified as CD37 (Workshop V, Code CD37.7). CD37 is strongly expressed on normal and neoplastic mature (sIg+) B-lymphocytes. In B-cell ontogeny, CD37 appears after the pre-B-cell stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells.1 CD37 is also present, at low densities, on resting and activated T cells, neutrophils, monocytes, and some myelomonocytic leukemia cells. It is absent from platelets, erythrocytes. CD37 is a member of a family of tetraspan transmembrane proteins, including CD9, CD53, CD63, CD81, and CD82. It associates other tetraspan transmembrane proteins and MHC class II molecules to form a large complex at the surface of B cells and play a role in signal transduction. CD37 is a valuable and stable marker for peripheral mature B-cells and corresponding malignancies like B-cell chronic lymphocytic leukemia (B-CLL), hairy cell leukemia (HCL), and all types of B-cell non-Hodgkin'' lymphoma (B-NHL). Gene Symbol: CD37///TSPAN26 
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                                            基因ID
- 951
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                                            UniProt
- P11049
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                                            途径
- Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
 抗原
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