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Keratin 10 抗体

KRT10 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN6297641
发货至: 中国
  • 抗原 See all Keratin 10 (KRT10) 抗体
    Keratin 10 (KRT10)
    适用
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    人, 小鼠
    宿主
    • 75
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    小鼠
    克隆类型
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    单克隆
    标记
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    This Keratin 10 antibody is un-conjugated
    应用范围
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    Immunohistochemistry (IHC)
    原理
    Mouse anti-Human/Mouse Cytokeratin 10 Antibody [IHC only]
    特异性
    Cytoplasmic
    纯化方法
    Skin extract from a human psoriasis patient was used as the immunogen for this Cytokeratin 10 antibody.
    免疫原
    Skin extract from a human psoriasis patient was used as the immunogen for this Cytokeratin 10 antibody.
    Top Product
    Discover our top product KRT10 Primary Antibody
  • 应用备注
    Prediluted format : incubate for 30 min at RT (2)
    限制
    仅限研究用
  • 缓冲液
    Prediluted in 1X PBS ( pH 7.4) with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原
    Keratin 10 (KRT10)
    别名
    Keratin, type I cytoskeletal 10 (KRT10 产品)
    别名
    BCIE antibody, BIE antibody, CK10 antibody, EHK antibody, K10 antibody, KPP antibody, D130054E02Rik antibody, K1C1 antibody, Krt-1.10 antibody, Krt1-10 antibody, Ka10 antibody, Ker10 antibody, KRT10 antibody, KRT25 antibody, KRT27 antibody, KRT28 antibody, keratin 10 antibody, keratin 10, type I S homeolog antibody, keratin, type I cytoskeletal 25 antibody, KRT10 antibody, Krt10 antibody, krt10.S antibody, LOC101085587 antibody
    背景

    Target Description: This antibody recognizes a protein of 56.5 kDa, identified as cytokeratin 10 (CK10). cytokeratin 10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of cytokeratin 10 strictly parallels the extent of differentiation, it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, cytokeratin 10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), cytokeratin 10 is detected very frequently. Expression of cytokeratin 10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.

    Gene Symbol: KRT10///KPP

    基因ID
    3858
    UniProt
    P13645
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