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Keratin 10 抗体

This anti-Keratin 10 antibody is a 小鼠 单克隆 antibody detecting Keratin 10 in IHC. Suitable for 人 和 小鼠.
产品编号 ABIN6297641
发货至: 中国

Quick Overview for Keratin 10 抗体 (ABIN6297641)

抗原

See all Keratin 10 (KRT10) 抗体
Keratin 10 (KRT10)

适用

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人, 小鼠

宿主

  • 103
  • 95
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小鼠

克隆类型

  • 137
  • 63
单克隆

标记

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This Keratin 10 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC)
  • 原理

    Mouse anti-Human/Mouse Cytokeratin 10 Antibody [IHC only]

    特异性

    Cytoplasmic

    纯化方法

    Skin extract from a human psoriasis patient was used as the immunogen for this Cytokeratin 10 antibody.

    免疫原

    Skin extract from a human psoriasis patient was used as the immunogen for this Cytokeratin 10 antibody.
  • 应用备注

    Prediluted format : incubate for 30 min at RT (2)

    限制

    仅限研究用
  • 缓冲液

    Prediluted in 1X PBS ( pH 7.4) with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    Keratin 10 (KRT10)

    别名

    Keratin, type I cytoskeletal 10

    背景

    Target Description: This antibody recognizes a protein of 56.5 kDa, identified as cytokeratin 10 (CK10). cytokeratin 10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of cytokeratin 10 strictly parallels the extent of differentiation, it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, cytokeratin 10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), cytokeratin 10 is detected very frequently. Expression of cytokeratin 10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.

    Gene Symbol: KRT10///KPP

    基因ID

    3858

    UniProt

    P13645
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