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NEFH 抗体

The 小鼠 单克隆 anti-NEFH antibody is suitable to detect NEFH in samples from 人, 大鼠 和 小鼠. It has been validated for IHC 和 FACS.
产品编号 ABIN6297632
发货至: 中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for NEFH 抗体 (ABIN6297632)

抗原

See all NEFH 抗体
NEFH (Neurofilament, Heavy Polypeptide (NEFH))

适用

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人, 大鼠, 小鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This NEFH antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Flow Cytometry (FACS)
  • 原理

    Mouse anti-Human/Mouse/Rat Neurofilament Antibody [Sodium Azide Free]

    特异性

    Cytoplasmic

    纯化方法

    Semi-purified human neurofilaments from spinal cord were used as the immunogen for the Neurofilament antibody.

    免疫原

    Semi-purified human neurofilaments from spinal cord were used as the immunogen for the Neurofilament antibody.
  • 应用备注

    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunohistochemistry (FFPE): 0.25-0.5 μg/mL for 30 min at RT (1)
    Prediluted format: incubate for 30 min at RT (2)

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    NEFH (Neurofilament, Heavy Polypeptide (NEFH))

    别名

    Neurofilament heavy polypeptide

    背景

    Target Description: This mAb reacts with a 200 kDa and 68 kDa protein, identified as heavy and light sub-units of neurofilaments (NF-H & NF-L). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68 kDa (NF-L), 160 kDa (NF-M) and 200 kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and cell carcinomas of the lung also express neurofilament.

    Gene Symbol: NEFH///KIAA0845///NFH

    基因ID

    4744

    UniProt

    P12036
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