TYR 抗体
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北京 101111
Quick Overview for TYR 抗体 (ABIN6297626)
抗原
See all TYR 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse anti-Human Tyrosinase Antibody [Sodium Azide Free]
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特异性
- Cytoplasmic
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纯化方法
- Recombinant tyrosinase protein was used as the immunogen for this Tyrosinase antibody.
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免疫原
- Recombinant tyrosinase protein was used as the immunogen for this Tyrosinase antibody.
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anti-Tyrosinase (TYR) (AA 20-340) antibody
TYR 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tyrosinase (TYR) (AA 1-377) antibodyTYR 适用: 人 WB, IF, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2A2-F4 unconjugated
anti-Tyrosinase (TYR) (AA 486-513) antibodyTYR 适用: 人 WB, IHC, IF, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Tyrosinase (TYR) antibodyTYR 适用: 人, 小鼠, 猴 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tyrosinase (TYR) (AA 1-377) antibodyTYR 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Tyrosinase (TYR) (C-Term) antibodyTYR 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tyrosinase (TYR) antibodyTYR 适用: 人 IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal T311 unconjugated
anti-Tyrosinase (TYR) (AA 486-513), (C-Term) antibodyTYR 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB19155 unconjugated
anti-Tyrosinase (TYR) antibodyTYR 适用: 人 WB, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal T311 unconjugated
anti-Tyrosinase (TYR) (C-Term) antibodyTYR 适用: 人 WB, IF, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2) -
限制
- 仅限研究用
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缓冲液
- In 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- TYR (Tyrosinase (TYR))
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别名
- Tyrosinase
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背景
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Target Description: Recognizes a cluster of proteins between 70-80 kDa, identified as tyrosinase. Occasionally a minor band at 55 kDa is also detected. This mAb shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway, the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Staining of melanomas with this mAb shows tyrosinase in melanotic as well as amelanotic variants. This mAb is a useful marker for melanocytes and melanomas.
Gene Symbol: TYR
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基因ID
- 7299
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UniProt
- P14679
抗原
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