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TYR 抗体

This anti-TYR antibody is a 小鼠 单克隆 antibody detecting TYR in IHC, IF 和 FACS. Suitable for 人.
产品编号 ABIN6297626
发货至: 中国

Quick Overview for TYR 抗体 (ABIN6297626)

抗原

See all TYR 抗体
TYR (Tyrosinase (TYR))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This TYR antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
  • 原理

    Mouse anti-Human Tyrosinase Antibody [Sodium Azide Free]

    特异性

    Cytoplasmic

    纯化方法

    Recombinant tyrosinase protein was used as the immunogen for this Tyrosinase antibody.

    免疫原

    Recombinant tyrosinase protein was used as the immunogen for this Tyrosinase antibody.
  • 应用备注

    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 1-2 μg/mL
    Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
    Prediluted format: incubate for 30 min at RT (2)

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    TYR (Tyrosinase (TYR))

    别名

    Tyrosinase

    背景

    Target Description: Recognizes a cluster of proteins between 70-80 kDa, identified as tyrosinase. Occasionally a minor band at 55 kDa is also detected. This mAb shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway, the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Staining of melanomas with this mAb shows tyrosinase in melanotic as well as amelanotic variants. This mAb is a useful marker for melanocytes and melanomas.

    Gene Symbol: TYR

    基因ID

    7299

    UniProt

    P14679
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