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NKX2-1 抗体

This anti-NKX2-1 antibody is a 小鼠 单克隆 antibody detecting NKX2-1 in IHC, FACS 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6297615
发货至: 中国

Quick Overview for NKX2-1 抗体 (ABIN6297615)

抗原

See all NKX2-1 抗体
NKX2-1 (NK2 Homeobox 1 (NKX2-1))

适用

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人, 小鼠, 大鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This NKX2-1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)
  • 原理

    Mouse anti-Human/Mouse/Rat TTF1 Antibody [Sodium Azide Free]

    特异性

    Nuclear

    纯化方法

    Recombinant protein was used as the immunogen for the TTF1 antibody.

    免疫原

    Recombinant protein was used as the immunogen for the TTF1 antibody.
  • 应用备注

    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 0.5-1 μg/mL
    Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
    Prediluted format: incubate for 30 min at RT (2)

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    NKX2-1 (NK2 Homeobox 1 (NKX2-1))

    别名

    Homeobox protein Nkx-2.1

    背景

    Target Description: Recognizes a protein of 40 kDa, identified as Thyroid transcription factor-1. TTF-1 is a member of the NKx2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver, stomach, pancreas, small intestine, colon, kidney, breast, skin, testes, pituitary, prostate, and adrenal glands are unreactive. Anti-TTF-1 is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the breast, mediastinal germ cell tumors, and malignant mesothelioma. It can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates. Loss of TTF-1 expression in non-small cell lung carcinoma has been associated with aggressive behavior of such neoplasms. TTF-1 reactivity is also seen in thyroid malignancies.

    Gene Symbol: NKX2-1///NKX2A///TITF1///TTF1

    基因ID

    7080

    UniProt

    P43699

    途径

    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Glucan Metabolic Process, Feeding Behaviour
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