NKX2-1 抗体
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- 抗原 See all NKX2-1 抗体
- NKX2-1 (NK2 Homeobox 1 (NKX2-1))
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适用
- 人, 小鼠, 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This NKX2-1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC)
- 原理
- Mouse anti-Human/Mouse/Rat TTF1 Antibody [IHC only]
- 特异性
- Nuclear
- 纯化方法
- Recombinant protein was used as the immunogen for the TTF1 antibody.
- 免疫原
- Recombinant protein was used as the immunogen for the TTF1 antibody.
- Top Product
- Discover our top product NKX2-1 Primary Antibody
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- 应用备注
- Prediluted format : incubate for 30 min at RT (2)
- 限制
- 仅限研究用
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- 缓冲液
- Prediluted in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide, For IHC use only
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- 抗原
- NKX2-1 (NK2 Homeobox 1 (NKX2-1))
- 别名
- Homeobox protein Nkx-2.1 (NKX2-1 产品)
- 别名
- BCH antibody, BHC antibody, NK-2 antibody, NKX2.1 antibody, NKX2A antibody, TEBP antibody, TITF1 antibody, TTF-1 antibody, TTF1 antibody, titf1-A antibody, Xnkx-2.1 antibody, NKX2-1 antibody, LOC100227803 antibody, AV026640 antibody, Nkx2.1 antibody, T/EBP antibody, Titf1 antibody, Ttf-1 antibody, nk2.1a antibody, nkx2.1 antibody, nkx2.4a antibody, titf1 antibody, titf1a antibody, NK2 homeobox 1 antibody, NK2 homeobox 1 L homeolog antibody, NK2 homeobox 4b antibody, NKX2-1 antibody, nkx2-1.L antibody, Nkx2-1 antibody, nkx2.4b antibody
- 背景
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Target Description: Recognizes a protein of 40 kDa, identified as Thyroid transcription factor-1. TTF-1 is a member of the NKx2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver, stomach, pancreas, small intestine, colon, kidney, breast, skin, testes, pituitary, prostate, and adrenal glands are unreactive. Anti-TTF-1 is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the breast, mediastinal germ cell tumors, and malignant mesothelioma. It can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates. Loss of TTF-1 expression in non-small cell lung carcinoma has been associated with aggressive behavior of such neoplasms. TTF-1 reactivity is also seen in thyroid malignancies.
Gene Symbol: NKX2-1///NKX2A///TITF1///TTF1
- 基因ID
- 7080
- UniProt
- P43699
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Systemic Arterial Blood Pressure by Hormones, Cellular Glucan Metabolic Process, Feeding Behaviour
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