ErbB2/Her2 抗体
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Quick Overview for ErbB2/Her2 抗体 (ABIN6297525)
抗原
See all ErbB2/Her2 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse anti-Human/Rat ErbB2 Antibody HER2 [Sodium Azide Free]
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特异性
- Extracellular/Intracellular cell membrane
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纯化方法
- Recombinant human protein was used as the immunogen for this ErbB2 antibody.(1)
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免疫原
- Recombinant human protein was used as the immunogen for this ErbB2 antibody.(1)
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应用备注
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FACS: 0.5-1 μg/million cells
IF: 0.5-1 μg/mL -
限制
- 仅限研究用
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缓冲液
- In 1X PBS ( pH 7.4), BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))
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别名
- Receptor tyrosine-protein kinase erbB-2
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背景
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Target Description: This antibody recognizes a protein of 185 kDa, which is identified as HER2 / ErbB2. Its epitope is localized in the extracellular domain. ErbB2 is a member of the EGFR family. This antibody is specific and shows minimal cross-reaction with other members of the EGFR-family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. ErbB2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary.
Gene Symbol: ERBB2///HER2///MLN19///NEU///NGL
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基因ID
- 2064
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UniProt
- P04626
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development
抗原
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