MLANA 抗体
Quick Overview for MLANA 抗体 (ABIN6297244)
抗原
See all MLANA 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse anti-Human/Mouse/Rat Melan-A Antibody [Sodium Azide Free]
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特异性
- Cytoplasmic
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纯化方法
- Recombinant human Melan-A protein was used as the immunogen for this antibody.
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免疫原
- Recombinant human Melan-A protein was used as the immunogen for this antibody.
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应用备注
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ELISA: order BSA-free format for coating
FACS: 0.5-1 μg/million cells
IF: 1-2 μg/mL
WB: 0.5-1 μg/mL
IP: 0.5-1 μg/500 μg protein lysate
IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2) -
限制
- 仅限研究用
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缓冲液
- In 1X PBS ( pH 7.4), BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- MLANA (Melan A (MLANA))
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别名
- Melanoma antigen recognized by T-cells 1
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背景
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Target Description: This antibody recognizes a protein doublet of 20-22 kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. There are seven other melanoma associated antigens recognized by autologous cytotoxic T cells: MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MART-1 antibody labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. The antibody does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
Gene Symbol: MLANA///MART1
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基因ID
- 2315
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UniProt
- Q16655
抗原
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