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Desmin 抗体

This anti-Desmin antibody is a 小鼠 单克隆 antibody detecting Desmin in WB, IHC, IF 和 FACS. Suitable for 人, 大鼠, 小鼠, 小鸡 和 Hamster.
产品编号 ABIN6297155
发货至: 中国

Quick Overview for Desmin 抗体 (ABIN6297155)

抗原

See all Desmin (DES) 抗体
Desmin (DES)

适用

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人, 大鼠, 小鼠, 小鸡, Hamster

宿主

  • 133
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小鼠

克隆类型

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单克隆

标记

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This Desmin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
  • 原理

    Mouse anti-Human/Mouse/Rat/Hamster/Chicken Desmin Antibody (Muscle cell marker) [Sodium Azide Free]

    特异性

    Cytoplasmic

    纯化方法

    Recombinant human Desmin was used as the immunogen for the Desmin antibody.

    免疫原

    Recombinant human Desmin was used as the immunogen for the Desmin antibody.
  • 应用备注

    WB: 0.5-1 μg/mL
    FACS: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 1-2 μg/mL
    Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    Desmin (DES)

    别名

    Desmin

    背景

    Target Description: Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain alpha-helical coiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of normal smooth, skeletal, and cardiac muscles. Antibody reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascular cells of glomus tumors of the skin.

    Gene Symbol: DES

    基因ID

    1674

    UniProt

    P17661
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