Desmin 抗体
Quick Overview for Desmin 抗体 (ABIN6297155)
抗原
See all Desmin (DES) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse anti-Human/Mouse/Rat/Hamster/Chicken Desmin Antibody (Muscle cell marker) [Sodium Azide Free]
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特异性
- Cytoplasmic
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纯化方法
- Recombinant human Desmin was used as the immunogen for the Desmin antibody.
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免疫原
- Recombinant human Desmin was used as the immunogen for the Desmin antibody.
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应用备注
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WB: 0.5-1 μg/mL
FACS: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Immunohistochemistry (FFPE): 1-2 μg/mL for 30 min at RT -
限制
- 仅限研究用
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缓冲液
- In 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- Desmin (DES)
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别名
- Desmin
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背景
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Target Description: Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain alpha-helical coiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of normal smooth, skeletal, and cardiac muscles. Antibody reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascular cells of glomus tumors of the skin.
Gene Symbol: DES
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基因ID
- 1674
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UniProt
- P17661
抗原
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