BAFF 抗体
Quick Overview for BAFF 抗体 (ABIN6297137)
抗原
See all BAFF (TNFSF13B) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse anti-Human BAFF Antibody / BLyS [Sodium Azide Free]
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特异性
- Cell surface, cytoplasmic
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纯化方法
- Recombinant human BAFF protein was used as the immunogen for this BAFF antibody.
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免疫原
- Recombinant human BAFF protein was used as the immunogen for this BAFF antibody.
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应用备注
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FACS: 0.5-1 μg/million cells
IF: 1-2 μg/mL -
限制
- 仅限研究用
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缓冲液
- In sterile PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- BAFF (TNFSF13B) (Tumor Necrosis Factor (Ligand) Superfamily, Member 13b (TNFSF13B))
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别名
- Tumor necrosis factor ligand superfamily member 13B
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背景
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Target Description: BAFF/BLyS/CD257 is a type II transmembrane protein, and a member of the tumor necrosis factor ligand superfamily. It is proteolytically cleaved to form a soluble protein. BAFF, like other TNF ligand family members, forms homo-trimers. The predicted molecular weight of a BAFF monomer is approximately 31 kDa. It is expressed on peripheral blood B and T lymphocytes, monocytes, macrophages, and dendritic cells and is upregulated by IFN-gamma and down-regulated by PMA/ionomycin treatment. BAFF stimulates B and T cell immunity and regulates humoral immunity by binding TACI and BCMA receptors, BAFF prevents apoptosis and promotes B cell survival by binding the BAFF-specific receptor (BAFFR/BR3).
Gene Symbol: TNFSF13B///BAFF///BLYS///TALL1///TNFSF20///ZTNF4///UNQ401///PRO738
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基因ID
- 10673
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UniProt
- Q9Y275
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途径
- NF-kappaB Signaling, Production of Molecular Mediator of Immune Response
抗原
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