IGHA1 抗体
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北京 101111
Quick Overview for IGHA1 抗体 (ABIN6296837)
抗原
适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse anti-Human IgA Antibody [Sodium Azide Free]
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特异性
- Cytoplasm, cell surface and secreted
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纯化方法
- Purified human alpha heavy chain was used as the immunogen for the Anti-IgA antibody.
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免疫原
- Purified human alpha heavy chain was used as the immunogen for the Anti-IgA antibody.
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anti-Immunoglobulin Heavy Constant alpha 1 (IGHA1) (AA 207-353) antibody
IGHA1 适用: 人, 猴, 小鼠 IHC, WB, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 7D5F12 unconjugated
anti-Immunoglobulin Heavy Constant alpha 1 (IGHA1) (AA 257-286), (C-Term) antibodyIGHA1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB18272 unconjugated
anti-Immunoglobulin Heavy Constant alpha 1 (IGHA1) (AA 257-286) antibodyIGHA1 适用: 人 IHC, WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Immunoglobulin Heavy Constant alpha 1 (IGHA1) antibodyIGHA1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Immunoglobulin Heavy Constant alpha 1 (IGHA1) antibodyIGHA1 适用: 人 IHC, WB, FACS 宿主: 兔 Polyclonal unconjugated
anti-Immunoglobulin Heavy Constant alpha 1 (IGHA1) (Internal Region) antibodyIGHA1 适用: 人 IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Immunoglobulin Heavy Constant alpha 1 (IGHA1) antibodyIGHA1 适用: 人 IHC, WB, IF, ICC, IP 宿主: 兔 Monoclonal AOII-9 unconjugated
anti-Immunoglobulin Heavy Constant alpha 1 (IGHA1) (C-Term) antibodyIGHA1 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Flow Cytometry: 1-2 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL 30 min RT
Immunohistochemistry (FFPE): 0.5-1 μg/mL 30 min RT (1) -
限制
- 仅限研究用
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缓冲液
- In 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- IGHA1 (Immunoglobulin Heavy Constant alpha 1 (IGHA1))
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别名
- Immunoglobulin heavy constant alpha 1
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背景
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Target Description: This mAb is specific to heavy chain of IgA and shows minimal cross-reaction with heavy chains of other immunoglobulins. It is reactive with all subclasses of Alpha heavy chain. Immunoglobulins are four-chain, Y-shaped, monomeric structures comprised of two identical heavy chains and two identical light chains held together through inter-chain disulfide bonds. The chains form two domains, the Fab (antigen binding) fragment and the Fc (constant) fragment. Immunoglobulin A (IgA) is the main protein of the mucosal immune system. It is generated by B-cells in gut-associated lymphoid tissues. Daily production of IgA exceeds that of any of the other immunoglobulins. IgA exists mainly in dimers but can also exist as polymers or as monomers. Dimers and polymers contain a joining (J) chain that can be bound by the polymeric immunoglobulin receptor (pIgR) for transportation of the molecule to mucosal surfaces. The most common feature of plasmacytomas, and certain non-Hodgkin s lymphomas is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
Gene Symbol: IGHA1///IGHA2
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UniProt
- P01876, P01877
抗原
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