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CD55 抗体

This anti-CD55 antibody is a 小鼠 单克隆 antibody detecting CD55 in FACS, IF 和 IHC (fro). Suitable for 人.
产品编号 ABIN6296784
发货至: 中国

Quick Overview for CD55 抗体 (ABIN6296784)

抗原

See all CD55 抗体
CD55 (Complement Decay-Accelerating Factor (CD55))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD55 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 原理

    Mouse anti-Human CD55 Antibody (DAF) [Sodium Azide Free]

    特异性

    Cell surface

    纯化方法

    PHA stimulated human PBL were used as the immunogen for the CD55 antibody.

    免疫原

    PHA stimulated human PBL were used as the immunogen for the CD55 antibody.
  • 应用备注

    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 0.5-1 μg/mL
    Immunohistochemistry (Frozen): 0.5-1 μg/mL for 30 min at RT

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    CD55 (Complement Decay-Accelerating Factor (CD55))

    别名

    Complement decay-accelerating factor

    背景

    Target Description: Recognizes a single chain glycoprotein of 70 kDa, identified as CD55 (also known as decay accelerating factor, DAF). CD55/DAF is widely expressed on cells throughout the body including leukocytes, erythrocytes, epithelium, endothelium, and fibroblasts. It is a Glycosyl phosphatidylinositol anchored (GPI-anchored) member of the membrane bound complement regulatory proteins that inhibit autologous complement cascade activation. It prevents the amplification steps of the complement cascade by interfering with the assembly of the C3-convertases, C4b2a and C3bBb, and the C5-convertase, C4b2a3b and C3bBb3b. CD55 also serves as receptor for CD97 and for echovirus and Coxsackie B virus. The mAb 143-30 can be used as marker for paroxysmal nocturnal hemoglobinuria (PNH).

    Gene Symbol: CD55///CR///DAF

    基因ID

    1604

    UniProt

    P08174

    途径

    Complement System, Regulation of Leukocyte Mediated Immunity
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