NGFR 抗体
Quick Overview for NGFR 抗体 (ABIN6296732)
抗原
See all NGFR 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse anti-Human/Non-Human Primates NGF Receptor Antibody Cocktail [Sodium Azide Free]
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特异性
- Cell surface and cytoplasmic
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纯化方法
- NGFR from A875 melanoma cells (NGFR5) and recombinant human protein (NTR/912) were used as the immunogen for the NGF Receptor antibody cocktail.
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免疫原
- NGFR from A875 melanoma cells (NGFR5) and recombinant human protein (NTR/912) were used as the immunogen for the NGF Receptor antibody cocktail.
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应用备注
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Western blot: 1-2 μg/mL
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2) -
限制
- 仅限研究用
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缓冲液
- In 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- NGFR (Nerve Growth Factor Receptor (NGFR))
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别名
- Tumor necrosis factor receptor superfamily member 16
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背景
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Target Description: It recognizes a glycoprotein of 75 kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). NGFR is expressed in various neural crest cells and their tumors such as melanocytes, melanomas, neuroblastomas, pheochromocytomas and neurofibromas. Reportedly, anti-NGFR is a reliable marker for desmoplastic and neurotropic melanomas. NGFR is expressed in mature non-neural cells such as perivascular cells, dental pulp cells, lymphoidal follicular dendritic cells, basal epithelium of oral mucosa and hair follicles, prostate basal cells, and myoepithelial cells. Anti-NGFR stains the myoepithelial cells of breast ducts and intra-lobular fibroblasts of breast ducts.
Gene Symbol: NGFR///TNFRSF16
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基因ID
- 4804
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UniProt
- P08138
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途径
- NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
抗原
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