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NGFR 抗体

This anti-NGFR antibody is a 小鼠 单克隆 antibody detecting NGFR in WB, FACS, IHC 和 IF. Suitable for 人 和 Non-Human Primate.
产品编号 ABIN6296732
发货至: 中国

Quick Overview for NGFR 抗体 (ABIN6296732)

抗原

See all NGFR 抗体
NGFR (Nerve Growth Factor Receptor (NGFR))

适用

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人, Non-Human Primate

宿主

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小鼠

克隆类型

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单克隆

标记

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This NGFR antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 原理

    Mouse anti-Human/Non-Human Primates NGF Receptor Antibody Cocktail [Sodium Azide Free]

    特异性

    Cell surface and cytoplasmic

    纯化方法

    NGFR from A875 melanoma cells (NGFR5) and recombinant human protein (NTR/912) were used as the immunogen for the NGF Receptor antibody cocktail.

    免疫原

    NGFR from A875 melanoma cells (NGFR5) and recombinant human protein (NTR/912) were used as the immunogen for the NGF Receptor antibody cocktail.
  • 应用备注

    Western blot: 1-2 μg/mL
    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 1-2 μg/mL
    Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
    Prediluted format: incubate for 30 min at RT (2)

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    NGFR (Nerve Growth Factor Receptor (NGFR))

    别名

    Tumor necrosis factor receptor superfamily member 16

    背景

    Target Description: It recognizes a glycoprotein of 75 kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). NGFR is expressed in various neural crest cells and their tumors such as melanocytes, melanomas, neuroblastomas, pheochromocytomas and neurofibromas. Reportedly, anti-NGFR is a reliable marker for desmoplastic and neurotropic melanomas. NGFR is expressed in mature non-neural cells such as perivascular cells, dental pulp cells, lymphoidal follicular dendritic cells, basal epithelium of oral mucosa and hair follicles, prostate basal cells, and myoepithelial cells. Anti-NGFR stains the myoepithelial cells of breast ducts and intra-lobular fibroblasts of breast ducts.

    Gene Symbol: NGFR///TNFRSF16

    基因ID

    4804

    UniProt

    P08138

    途径

    NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
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