CD1b 抗体
Quick Overview for CD1b 抗体 (ABIN6296508)
抗原
See all CD1b (CD1B) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse anti-Human CD1b Antibody [Sodium Azide Free]
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特异性
- Cell surface
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纯化方法
- Human peripheral lymphocytes were used as the immunogen for this CD1b antibody.
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免疫原
- Human peripheral lymphocytes were used as the immunogen for this CD1b antibody.
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应用备注
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Functional testing: order BSA/azide free format
IF: 0.5-1 μg/mL
FACS: 0.5-1 μg/million cells in 0.1ml -
限制
- 仅限研究用
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缓冲液
- In 1X PBS ( pH 7.4), BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- CD1b (CD1B)
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别名
- T-cell surface glycoprotein CD1b
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背景
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Target Description: This antibody recognizes CD1b, a 44 kDa type I glycoprotein associated with beta2-microglobulin. It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells. The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. Constitutive endocytosis of CD1b molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. It is also expressed in interdigitating cells.
Gene Symbol: CD1B
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基因ID
- 910
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UniProt
- P29016
抗原
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