Myeloid Cell Marker 抗体
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Quick Overview for Myeloid Cell Marker 抗体 (ABIN6296505)
抗原
适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse anti-Human Myeloid Cell Marker Antibody [Sodium Azide Free]
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特异性
- Cytoplasmic and nuclear
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纯化方法
- Human peripheral blood mononuclear cells were used as the immunogen for this Myeloid cell marker antibody.
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免疫原
- Human peripheral blood mononuclear cells were used as the immunogen for this Myeloid cell marker antibody.
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anti-Myeloid Cell Marker antibody
适用: 人 FACS, IF, IHC (p) 宿主: 小鼠 Monoclonal BM-1 unconjugated
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应用备注
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FACS: 0.5-1 μg/million cells
IF: 1-2 μg/mL
IHC (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2) -
限制
- 仅限研究用
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缓冲液
- In 1X PBS ( pH 7.4), BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- Myeloid Cell Marker
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背景
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Target Description: This antibody recognizes a 183 kDa protein with DNA-binding characteristics, which is identified as a myeloid cell specific antigen. Clone BM-1 antibody reacts with myeloid precursor cells and granulocytes in bone marrow. Its antigen appears to be restricted to M2 and M3 acute myelogenous leukemia (AML) subtypes. This type of marker is useful in the identification of different levels of cellular differentiation. BM-1 and BM-2 antibodies react with early precursor and mature forms of human myeloid cells. This mAb is useful in the identification of myelogenous leukemias, distinguishing granulocytic sarcomas from lymphoid malignancies and also in the study of differentiation and transformation of human myeloid cells. The biological function of the marker protein is not clear, although it has been proposed that it may play a role in cell differentiation.
抗原
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