CD35 抗体
Quick Overview for CD35 抗体 (ABIN6296464)
抗原
See all CD35 (CR1) 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse anti-Human/Baboon/Cynomolgus Monkey/Rhesus Monkey CD35 Antibody (Complement Receptor 1) [Sodium Azide Free]
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特异性
- Cell surface
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纯化方法
- Human monocytes were used as the immunogen for this CD35 antibody.
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免疫原
- Human monocytes were used as the immunogen for this CD35 antibody.
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应用备注
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Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 minutes at RT (1)
Prediluted format: incubate for 30 min at RT (2) -
限制
- 仅限研究用
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缓冲液
- In 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- CD35 (CR1) (Complement Component Receptor 1 (CD35) (CR1))
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别名
- Complement receptor type 1
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背景
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Target Description: Recognizes a protein of 210-220 kDa, which is identified as the Complement receptor 1 or CD35. This mAb is specific for a site in CR1 that is distal from the C3b-binding site, so that it is unable to block CR1/CD35 activity. It is highly specific and shows no cross-reaction with CR2/CD21. The primary function of CR1 is to serve as the cellular receptor for C3b and C4b, the most important components of the complement system leading to clearance of foreign macromolecules. The Knops blood group system is a system of antigens located on this protein. Follicular dendritic cells (FDC) are restricted to the B-cell regions of secondary lymphoid follicles. They are CD21+/CD35+/CD1a-. This mAb labels follicular dendritic cells and follicular dendritic cell sarcoma.
Gene Symbol: CR1///C3BR
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基因ID
- 1378
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UniProt
- P17927
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途径
- Complement System, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Endopeptidase Activity
抗原
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