ACTN2 抗体 (C-Term)
(1 reference)Quick Overview for ACTN2 抗体 (C-Term) (ABIN629641)
抗原
See all ACTN2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- Alpha Actinin 2 antibody was raised against the C terminal of ACTN2
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纯化方法
- Purified
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免疫原
- alpha Actinin 2 antibody was raised using the C terminal of ACTN2 corresponding to a region with amino acids VIASFRILASDKPYILAEELRRELPPDQAQYCIKRMPAYSGPGSVPGALD
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anti-Actinin, alpha 2 (ACTN2) antibody
ACTN2 适用: 人 WB, IHC, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 2 (ACTN2) (AA 1-254) antibodyACTN2 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 2 (ACTN2) (AA 557-692) antibodyACTN2 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal ACTN2-3293 unconjugated
anti-Actinin, alpha 2 (ACTN2) (AA 557-692) antibodyACTN2 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal ACTN2-3292 unconjugated
anti-Actinin, alpha 2 (ACTN2) (AA 557-692) antibodyACTN2 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal ACTN2-3291 unconjugated
anti-Actinin, alpha 2 (ACTN2) (N-Term) antibodyACTN2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 2 (ACTN2) antibodyACTN2 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 2 (ACTN2) (AA 11-347) antibodyACTN2 适用: 人, 小鼠 WB, IHC, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 2 (ACTN2) (AA 1-250) antibodyACTN2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 2 (ACTN2) (C-Term) antibodyACTN2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB: 1.25 µg/mL, IHC: 4-8 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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Alpha Actinin 2 Blocking Peptide, (ABIN5612032), is also available for use as a blocking control in assays to test for specificity of this Alpha Actinin 2 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of ACTN2 antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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: "Force Generation via β-Cardiac Myosin, Titin, and α-Actinin Drives Cardiac Sarcomere Assembly from Cell-Matrix Adhesions." in: Developmental cell, Vol. 44, Issue 1, pp. 87-96.e5, (2018) (PubMed).
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: "Force Generation via β-Cardiac Myosin, Titin, and α-Actinin Drives Cardiac Sarcomere Assembly from Cell-Matrix Adhesions." in: Developmental cell, Vol. 44, Issue 1, pp. 87-96.e5, (2018) (PubMed).
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- ACTN2 (Actinin, alpha 2 (ACTN2))
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别名
- alpha Actinin 2
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背景
- The alpha-actinins are a multigene family of four actin-binding proteins related to dystrophin. The two skeletal muscle isoforms of alpha-actinin (ACTN2 and ACTN3) are major structural components of the Z-line involved in anchoring the actin-containing thin filaments. In humans, ACTN2 is expressed in all muscle fibres, while ACTN3 expression is restricted to a subset of type 2 fibres. Murine Actn2 and Actn3 are differentially expressed, spatially and temporally, during embryonic development and, in contrast to humans, alpha-actinin-2 expression does not completely overlap alpha-actinin-3 in postnatal skeletal muscle, suggesting independent function.
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分子量
- 98 kDa (MW of target protein)
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途径
- Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Negative Regulation of Transporter Activity
抗原
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