PRP19 抗体
Quick Overview for PRP19 抗体 (ABIN629622)
抗原
See all PRP19 (PRPF19) 抗体适用
宿主
克隆类型
标记
应用范围
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纯化方法
- Purified
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免疫原
- PRPF19 antibody was raised using a synthetic peptide corresponding to a region with amino acids PSVVGAGEPMDLGELVGMTPEIIQKLQDKATVLTTERKKRGKTVPEELVK
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应用备注
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WB: 2.5 µg/mL, IHC: 4-8 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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PRPF19 Blocking Peptide, (ABIN5615578), is also available for use as a blocking control in assays to test for specificity of this PRPF19 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Lyophilized powder. Add distilled water for a 1 mg/mL concentration of PRPF19 antibody in PBS
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浓度
- Lot specific
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缓冲液
- PBS
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2-8 °C for short periods. For longer periods of storage, store at -20 °C.
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- PRP19 (PRPF19) (Pre-mRNA Processing Factor 19 (PRPF19))
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别名
- PRPF19
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背景
- PRPF19 plays a role in DNA double-strand break (DSB) repair and pre-mRNA splicing reaction. It binds double-stranded DNA in a sequence-nonspecific manner. PRPF19 acts as a structural component of the nuclear framework. It may also serve as a support for spliceosome binding and activity. It is essential for spliceosome assembly in a oligomerization-dependent manner and might also be important for spliceosome stability. It also may have E3 ubiquitin ligase activity.
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分子量
- 55 kDa (MW of target protein)
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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