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Keratin 10 抗体

This anti-Keratin 10 antibody is a 小鼠 单克隆 antibody detecting Keratin 10 in IHC, FACS 和 IF. Suitable for 人, 犬 和 Cat.
产品编号 ABIN6295936
发货至: 中国

Quick Overview for Keratin 10 抗体 (ABIN6295936)

抗原

See all Keratin 10 (KRT10) 抗体
Keratin 10 (KRT10)

适用

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人, 犬, Cat

宿主

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小鼠

克隆类型

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  • 63
单克隆

标记

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This Keratin 10 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)
  • 原理

    Mouse anti-Human/Dog/Cat Cytokeratin 10 Antibody [Sodium Azide Free]

    特异性

    Cytoplasmic

    纯化方法

    A cytoskeletal preparation extracted from human ectocervical epithelium was used as the immunogen for the Cytokeratin 10 antibody.

    免疫原

    A cytoskeletal preparation extracted from human ectocervical epithelium was used as the immunogen for the Cytokeratin 10 antibody.
  • 应用备注

    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 0.5-1 μg/mL
    Immunohistochemistry (FFPE): 0.1-0.2 μg/mL for 30 min at RT

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    Keratin 10 (KRT10)

    别名

    Keratin, type I cytoskeletal 10

    背景

    Target Description: This mAb recognizes a protein of 56.5 kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation, it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.

    Gene Symbol: KRT10///KPP

    基因ID

    3858

    UniProt

    P13645
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