CD6 抗体
Quick Overview for CD6 抗体 (ABIN6295928)
抗原
See all CD6 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse anti-Human/Mouse CD6 Antibody [Sodium Azide Free]
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特异性
- Cell surface and cytoplasmic
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纯化方法
- A CD8+ cytotoxic T-cell clone was used as the immunogen for the CD6 antibody.
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免疫原
- A CD8+ cytotoxic T-cell clone was used as the immunogen for the CD6 antibody.
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应用备注
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Western blot: 1-2 μg/mL
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL -
限制
- 仅限研究用
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缓冲液
- In 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- CD6
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别名
- T-cell differentiation antigen CD6
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背景
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Target Description: CD6 is a type I transmembrane glycoprotein that contains a 24-amino acid signal sequence, three extracellular "scavenger receptor cysteine-rich" (SRCR) domains, a membrane-spanning domain and a 44-amino acid cytoplasmic domain. The CD6 glycoprotein is tyrosine phosphorylated during TCR-mediated T cell activation. CD6 shows significant homology to CD5. CD6 is present on mature thymocytes, peripheral T cells and a subset of B cells. Antibodies to CD6 are used to deplete T cells from bone marrow transplants to prevent graft versus host disease.
Gene Symbol: CD6
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基因ID
- 923
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UniProt
- P30203
抗原
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