CD81 抗体
Quick Overview for CD81 抗体 (ABIN6295927)
抗原
See all CD81 抗体适用
宿主
克隆类型
标记
应用范围
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原理
- Mouse anti-Human/Mouse/Rat CD81 Antibody [Sodium Azide Free]
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特异性
- Cytoplasmic, membranous
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纯化方法
- A B-cell line derived from a Burkitt lymphoma was used as the immunogen for the CD81 antibody.
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免疫原
- A B-cell line derived from a Burkitt lymphoma was used as the immunogen for the CD81 antibody.
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应用备注
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Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 0.5-1 μg/mL
WB: 0.5-1 μg/mL
Functional Studies: order BSA free formulation
IHC (FFPE): 0.5-1 μg/mL for 30 min at RT -
限制
- 仅限研究用
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缓冲液
- In 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- CD81
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别名
- CD81 antigen
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背景
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Target Description: This mAb recognizes a protein of 26 kDa, identified as CD81 (Workshop VI, Code CD81.1). CD81 has a very broad cellular distribution, being expressed on T- and B-lymphocytes, NK cells, thymocytes, eosinophils, fibroblasts, epithelial and endothelial cells. Neutrophils, erythrocytes and platelets are negative, while monocytes are variably positive. CD81 is a member of a family of tetraspans transmembrane proteins, including CD9, CD37, CD53, CD63, and CD82. It associates with CD19, CD21, Leu 13, and integrins on cell membrane and is involved in signal transduction in B lymphocyte development and cell adhesion. CD81 also acts as a receptor for the envelope protein E2 of chronic hepatitis C virus. Antibodies to CD81 have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas.
Gene Symbol: CD81///TAPA1///TSPAN28
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基因ID
- 975
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UniProt
- P60033
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途径
- Inositol Metabolic Process, Hepatitis C
抗原
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