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CD81 抗体

This anti-CD81 antibody is a 小鼠 单克隆 antibody detecting CD81 in FACS, WB, IHC, IF 和 Func. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6295927
发货至: 中国

Quick Overview for CD81 抗体 (ABIN6295927)

抗原

See all CD81 抗体
CD81

适用

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人, 小鼠, 大鼠

宿主

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小鼠

克隆类型

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单克隆

标记

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This CD81 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Functional Studies (Func)
  • 原理

    Mouse anti-Human/Mouse/Rat CD81 Antibody [Sodium Azide Free]

    特异性

    Cytoplasmic, membranous

    纯化方法

    A B-cell line derived from a Burkitt lymphoma was used as the immunogen for the CD81 antibody.

    免疫原

    A B-cell line derived from a Burkitt lymphoma was used as the immunogen for the CD81 antibody.
  • 应用备注

    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 0.5-1 μg/mL
    WB: 0.5-1 μg/mL
    Functional Studies: order BSA free formulation
    IHC (FFPE): 0.5-1 μg/mL for 30 min at RT

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    CD81

    别名

    CD81 antigen

    背景

    Target Description: This mAb recognizes a protein of 26 kDa, identified as CD81 (Workshop VI, Code CD81.1). CD81 has a very broad cellular distribution, being expressed on T- and B-lymphocytes, NK cells, thymocytes, eosinophils, fibroblasts, epithelial and endothelial cells. Neutrophils, erythrocytes and platelets are negative, while monocytes are variably positive. CD81 is a member of a family of tetraspans transmembrane proteins, including CD9, CD37, CD53, CD63, and CD82. It associates with CD19, CD21, Leu 13, and integrins on cell membrane and is involved in signal transduction in B lymphocyte development and cell adhesion. CD81 also acts as a receptor for the envelope protein E2 of chronic hepatitis C virus. Antibodies to CD81 have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas.

    Gene Symbol: CD81///TAPA1///TSPAN28

    基因ID

    975

    UniProt

    P60033

    途径

    Inositol Metabolic Process, Hepatitis C
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