TIMP2 抗体 (N-Term)
Quick Overview for TIMP2 抗体 (N-Term) (ABIN6295483)
抗原
See all TIMP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Mouse anti-Human/Mouse/Rat TIMP2 Antibody [Sodium Azide Free]
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特异性
- Cytoplasmic, cell surface, secreted
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纯化方法
- An amino acid sequence from the N-terminal region of the human protein was used as the immunogen for this TIMP2 antibody.
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免疫原
- An amino acid sequence from the N-terminal region of the human protein was used as the immunogen for this TIMP2 antibody.
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应用备注
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IHC (FFPE): 0.5-1 μg/mL for 30 min at RT
WB: 0.5-1 μg/mL
IF: 1-2 μg/mL -
限制
- 仅限研究用
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缓冲液
- In 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))
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别名
- Metalloproteinase inhibitor 2
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背景
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Target Description: It recognizes a protein of 21 kDa, identified as tissue inhibitor of metalloproteinases 2 (TIMP2). It is closely related to TIMP1 and shows the highest binding affinity to both the latent (pro) and active forms of 72 kDa Type IV collagenase (also known as MMP2 or gelatinase A). It also has affinity for the active form of 92 kDa Type IV collagenase (also known as MMP9 or gelatinase B). TIMP2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
Gene Symbol: TIMP2
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基因ID
- 7077
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UniProt
- P16035
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途径
- cAMP Metabolic Process
抗原
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