LHCGR 抗体 (N-Term)
Quick Overview for LHCGR 抗体 (N-Term) (ABIN6295469)
抗原
See all LHCGR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- Mouse anti-Human hCG Receptor / LH Receptor Antibody [Sodium Azide Free]
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特异性
- Cytoplasmic, cell surface
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纯化方法
- A partial recombinant protein from the N-terminal region of human Luteinizing hormone / Choriogonadotropin receptor was used as the immunogen for the hCG Receptor antibody.
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免疫原
- A partial recombinant protein from the N-terminal region of human Luteinizing hormone / Choriogonadotropin receptor was used as the immunogen for the hCG Receptor antibody.
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应用备注
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FACS: 0.5-1 μg/million cells in 0.1ml
IF: 1-2 μg/mL
WB: 0.5-1 μg/mL -
限制
- 仅限研究用
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缓冲液
- In 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))
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别名
- Lutropin-choriogonadotropic hormone receptor
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背景
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Target Description: Recognizes a protein of 78-85 kDa, which is identified as the receptor for Luteinizing hormone / Choriogonadotropin. Luteinizing hormone plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Choriogonadotropin production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone / choriogonadotropin receptor (LHCGR) as a seven transmembrane, G protein-coupled receptor glycoprotein. LHCGR influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of LHCGR on breast carcinoma correlates in part to the degree of tumor differentiation. LHCGR -positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women.
Gene Symbol: LHCGR///LCGR///LGR2///LHRHR
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基因ID
- 3973
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UniProt
- P22888
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途径
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, cAMP Metabolic Process, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
抗原
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