AIRE 抗体 (Center)
Quick Overview for AIRE 抗体 (Center) (ABIN6295388)
抗原
See all AIRE 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 64-92, Center
-
原理
- Rabbit Anti-AIRE (Center) Antibody
-
免疫原
- This AIRE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-92 amino acids from the Central region of human AIRE.
-
-
-
-
限制
- 仅限研究用
-
-
-
储存条件
- 4 °C,-20 °C
-
储存方法
- 2-8°C (short-term), -20°C (long-term)
-
-
- AIRE (Autoimmune Regulator (AIRE))
-
别名
- AIRE
-
背景
-
Target Description: This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CBP. At least three splice variant mRNAs products have been described including one which results in a premature stop codon and a transcript predicted to be a candidate for nuclear-mediated decay (NMD). Defects in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED).
Gene Symbol: AIRE
-
基因ID
- 326
-
UniProt
- O43918
-
途径
- Chromatin Binding
抗原
-