ISL1 抗体 (Center)
Quick Overview for ISL1 抗体 (Center) (ABIN6295190)
抗原
See all ISL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 156-185, Center
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原理
- Rabbit Anti-ISL1 (Center) Antibody
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免疫原
- This ISL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-185 amino acids from the Central region of human ISL1.
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限制
- 仅限研究用
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- ISL1 (ISL LIM Homeobox 1 (ISL1))
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别名
- ISL1
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背景
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Target Description: ISL1 is a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young.
Gene Symbol: ISL1
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基因ID
- 3670
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UniProt
- P61371
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途径
- Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
抗原
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