VLDLR 抗体 (C-Term)
Quick Overview for VLDLR 抗体 (C-Term) (ABIN6294641)
抗原
See all VLDLR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Mouse anti-Human/Rat VLDLR Antibody [Sodium Azide Free]
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特异性
- Cytoplasmic
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纯化方法
- A human partial recombinant protein from the C-terminal region was used as the immunogen for this VLDLR antibody.
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免疫原
- A human partial recombinant protein from the C-terminal region was used as the immunogen for this VLDLR antibody.
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应用备注
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FACS: 0.5-1 μg/10^6 cells
IF: 1-2 μg/mL
Western blot: 1-2 μg/mL
IHC (FFPE): 1-2 μg/mL (1) -
限制
- 仅限研究用
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缓冲液
- In 1X PBS ( pH 7.4), BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))
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别名
- Very low-density lipoprotein receptor
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背景
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Target Description: Very Low Density Lipoprotein Receptor (VLDLR/VLDL receptor) is a member of the LDL receptor gene family which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. VLDLR associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR. VLDL receptor is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development.
Gene Symbol: VLDLR
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基因ID
- 7436
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UniProt
- P98155
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途径
- Cellular Response to Molecule of Bacterial Origin
抗原
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