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TFF1 抗体 (C-Term)

This anti-TFF1 antibody is a 小鼠 单克隆 antibody detecting TFF1 in IHC, IF 和 FACS. Suitable for 人 和 猴.
产品编号 ABIN6294640
发货至: 中国

Quick Overview for TFF1 抗体 (C-Term) (ABIN6294640)

抗原

See all TFF1 抗体
TFF1 (Trefoil Factor 1 (TFF1))

适用

  • 88
  • 17
  • 17
  • 13
  • 11
人, 猴

宿主

  • 53
  • 47
小鼠

克隆类型

  • 51
  • 49
单克隆

标记

  • 64
  • 7
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
This TFF1 antibody is un-conjugated

应用范围

  • 60
  • 46
  • 35
  • 29
  • 19
  • 18
  • 14
  • 9
  • 6
  • 6
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
  • 抗原表位

    • 29
    • 16
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    原理

    Mouse anti-Human/Monkey TFF1 Antibody [Sodium Azide Free]

    特异性

    Cytoplasmic

    纯化方法

    A C-terminus peptide was used as the immunogen for the TFF1 antibody.

    免疫原

    A C-terminus peptide was used as the immunogen for the TFF1 antibody.
  • 应用备注

    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 0.5-1 μg/mL
    Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
    Prediluted format: incubate for 30 min at RT (2)

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    TFF1 (Trefoil Factor 1 (TFF1))

    别名

    Trefoil factor 1

    背景

    Target Description: It recognizes a polypeptide of 6.5 kDa, identified as pS2 estrogen-regulated protein. Its epitope is located in the c-terminus of human pS2 protein. pS2 is a trefoil peptide. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intra-chain disulfide bonds, forming the trefoil motif, or P-domain. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. About 60 % of breast carcinomas are positive for pS2. Staining is cytoplasmic, often with localization to the Golgi apparatus. pS2 is shown to be localized in normal stomach mucosa, gastric fluid, goblet cells in the colon and small intestine, and in ulcerations of the gastrointestinal tract. Several studies have shown that pS2 is primarily expressed in estrogen receptor-positive breast tumors and it may define a subset of estrogen-dependent tumors that displays an increased likelihood of response to endocrine therapy.

    Gene Symbol: TFF1///BCEI///PS2

    基因ID

    7031

    UniProt

    P04155

    途径

    EGFR Signaling Pathway
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