TIMP2 抗体 (AA 56-66)
Quick Overview for TIMP2 抗体 (AA 56-66) (ABIN6294556)
抗原
See all TIMP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 56-66
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原理
- Mouse anti-Human/Mouse/Rat/Guinea pig/Rabbit/Cow/Zebrafish TIMP2 Antibody [Sodium Azide Free]
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特异性
- Cytoplasmic, cell surface, secreted
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纯化方法
- Amino acids 56-66 (DSGNDIYGNPI) from the human protein were used as the immunogen for this TIMP-2 antibody.
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免疫原
- Amino acids 56-66 (DSGNDIYGNPI) from the human protein were used as the immunogen for this TIMP-2 antibody.
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应用备注
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IHC (FFPE): 0.5-1 μg/mL for 30 min at RT
WB: 0.5-1 μg/mL
IF: 1-2 μg/mL -
限制
- 仅限研究用
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缓冲液
- In 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))
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别名
- Metalloproteinase inhibitor 2
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背景
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Target Description: It recognizes a protein of 21 kDa, identified as tissue inhibitor of metalloproteinases-2 (TIMP-2). It is closely related to TIMP-1 and shows the highest binding affinity to both the latent (pro) and active forms of 72 kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92 kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
Gene Symbol: TIMP2
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基因ID
- 7077
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UniProt
- P16035
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途径
- cAMP Metabolic Process
抗原
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