Involucrin 抗体 (AA 421-568)
Quick Overview for Involucrin 抗体 (AA 421-568) (ABIN6294531)
抗原
See all Involucrin (IVL) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 421-568
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原理
- Mouse anti-Human/Gorilla/Owl Monkey/Pig/Dog Involucrin Antibody [Sodium Azide Free]
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特异性
- Cytoplasmic
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纯化方法
- Purified involucrin from human keratinocytes was used as the immunogen for this Involucrin antibody. Its epitope maps between amino acids 421-568 of human involucrin.
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免疫原
- Purified involucrin from human keratinocytes was used as the immunogen for this Involucrin antibody. Its epitope maps between amino acids 421-568 of human involucrin.
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应用备注
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Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Immunohistochemistry (FFPE): 0.1-0.2 μg/mL for 30 min at RT (1)
Prediluted format: incubate for 30 min at RT (2) -
限制
- 仅限研究用
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缓冲液
- In 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- Involucrin (IVL)
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别名
- Involucrin
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背景
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Target Description: Involucrin is expressed in a range of stratified squamous epithelia, including the cornea, which lacks a distinct cornified layer. In normal epidermis, it is first expressed in the upper spinous layers, and in keratinocyte cultures, all cells that have left the basal layer express it. Involucrin expression is altered in pathological conditions: in psoriasis and other benign epidermal hyperplasias, involucrin expression begins closer to the basal layer than normal, expression is abnormal in squamous cell carcinomas and premalignant lesions, and is reduced in severe dysplasias of the larynx and cervix.
Gene Symbol: IVL
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基因ID
- 3713
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UniProt
- P07476
抗原
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