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c-MYC 抗体 (AA 408-439)

The 小鼠 单克隆 anti-c-MYC antibody (ABIN6294516) specifically detects c-MYC in IF 和 FACS. The antibody is reactive with 人, Chimpanzee 和 Gorilla samples.
产品编号 ABIN6294516
发货至: 中国
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Quick Overview for c-MYC 抗体 (AA 408-439) (ABIN6294516)

抗原

See all c-MYC (MYC) 抗体
c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

适用

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人, Chimpanzee, Gorilla

宿主

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小鼠

克隆类型

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单克隆

标记

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This c-MYC antibody is un-conjugated

应用范围

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Immunofluorescence (IF), Flow Cytometry (FACS)
  • 抗原表位

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    AA 408-439

    原理

    Mouse anti-Human/Chimpanzee/Gorilla c-Myc Antibody [Sodium Azide Free]

    特异性

    Nuclear

    纯化方法

    Amino acids 408-439 (AEEQKLISEEDLLRKRREQLKHKLEQLRNSCA) from the human protein were used as the immunogen for this c-Myc antibody.

    免疫原

    Amino acids 408-439 (AEEQKLISEEDLLRKRREQLKHKLEQLRNSCA) from the human protein were used as the immunogen for this c-Myc antibody.
  • 应用备注

    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 1-2 μg/mL

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    c-MYC (MYC) (Myc Proto-Oncogene protein (MYC))

    别名

    Myc proto-oncogene protein

    背景

    Target Description: The c-Myc protein is a transcription factor, which is encoded by the c-Myc gene on human chromosome 8q24. c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin dependent kinase, ERK2 and C-Jun N terminal Kinase (JNK) in cell proliferation and cell cycle regulation. Studies also have shown that c-Myc is essential for tumor cell development in vasculogenesis and angiogenesis that distribute blood throughout the cells, and which brought extensive attention in the development of new therapeutic approach for cancer treatment.

    Gene Symbol: MYC///BHLHE39

    基因ID

    4609

    UniProt

    P01106

    途径

    p53 Pathway, Cell Division Cycle, Sensory Perception of Sound, Transition Metal Ion Homeostasis, Mitotic G1-G1/S Phases, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus, Warburg Effect
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