SOX2 抗体 (AA 176-305)
Quick Overview for SOX2 抗体 (AA 176-305) (ABIN6294339)
抗原
See all SOX2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 176-305
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原理
- Mouse anti-Human SOX2 Antibody [Sodium Azide Free]
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特异性
- Cytoplasmic, nuclear
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纯化方法
- Amino acids 176-305 of the human protein were used as the immunogen for the SOX-2 antibody.
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免疫原
- Amino acids 176-305 of the human protein were used as the immunogen for the SOX-2 antibody.
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应用备注
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ELISA: 2-4 μg/mL, order BSA-free formulation for coating
Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
Immunofluorescence: 1-2 μg/mL
Western blot: 0.5-1 μg/mL
Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT -
限制
- 仅限研究用
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缓冲液
- In 1X PBS, BSA free, sodium azide free
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储存液
- Azide free
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
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- SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
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别名
- Transcription factor SOX-2
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背景
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Target Description: SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. At present, 30 Sox genes have been identified. SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression.
Gene Symbol: SOX2
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基因ID
- 6657
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UniProt
- P48431
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途径
- Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
抗原
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