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Androgen Receptor 抗体 (AA 151-350)

The 小鼠 单克隆 anti-Androgen Receptor antibody (ABIN6294321) specifically detects Androgen Receptor in IHC, IF 和 FACS. The antibody is reactive with 人 samples.
产品编号 ABIN6294321
发货至: 中国
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Quick Overview for Androgen Receptor 抗体 (AA 151-350) (ABIN6294321)

抗原

See all Androgen Receptor (AR) 抗体
Androgen Receptor (AR)

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Androgen Receptor antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)
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    AA 151-350

    原理

    Mouse anti-Human Androgen Receptor Antibody [Sodium Azide Free]

    特异性

    Nuclear

    纯化方法

    A recombinant partial-length human AR protein corresponding to amino acids 151-350 was used as the immunogen for the Androgen Receptor antibody.

    免疫原

    A recombinant partial-length human AR protein corresponding to amino acids 151-350 was used as the immunogen for the Androgen Receptor antibody.
  • 应用备注

    Flow Cytometry: 0.5-1 μg/million cells in 0.1ml
    Immunofluorescence: 0.5-1 μg/mL
    Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1)
    Prediluted format: incubate for 30 min at RT (2)

    限制

    仅限研究用
  • 缓冲液

    In 1X PBS, BSA free, sodium azide free

    储存液

    Azide free

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.
  • 抗原

    Androgen Receptor (AR)

    别名

    Androgen receptor

    背景

    Target Description: Recognizes a protein of 110 kDa, which is identified as androgen receptor (AR). It reacts with full length, and the newly described A form of the receptor. It does not cross react with estrogen, progesterone, or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer, AR has been proposed, as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin. This mAb is superb for staining of formalin/paraffin tissues.

    Gene Symbol: AR///DHTR///NR3C4

    基因ID

    367

    UniProt

    P10275

    途径

    Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
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