KISS1 抗体 (Internal Region)
Quick Overview for KISS1 抗体 (Internal Region) (ABIN6266238)
抗原
See all KISS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- KISS1 Antibody detects endogenous levels of total KISS1.
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预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human KISS1, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-KiSS-1 Metastasis-Suppressor (KISS1) (AA 46-145) antibody
KISS1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1F7 unconjugated
anti-KiSS-1 Metastasis-Suppressor (KISS1) (AA 20-52) antibodyKISS1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB53797 unconjugated
anti-KiSS-1 Metastasis-Suppressor (KISS1) (AA 20-138) antibodyKISS1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-KiSS-1 Metastasis-Suppressor (KISS1) (AA 115-145) antibodyKISS1 适用: 人 WB, IF 宿主: 兔 Polyclonal RB53799 unconjugated
anti-KiSS-1 Metastasis-Suppressor (KISS1) (AA 1-126) antibodyKISS1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-KiSS-1 Metastasis-Suppressor (KISS1) (AA 20-138) antibodyKISS1 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-KiSS-1 Metastasis-Suppressor (KISS1) (AA 20-138) antibodyKISS1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-KiSS-1 Metastasis-Suppressor (KISS1) antibodyKISS1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-KiSS-1 Metastasis-Suppressor (KISS1) (AA 1-138) antibodyKISS1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-KiSS-1 Metastasis-Suppressor (KISS1) (AA 1-138) antibodyKISS1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:20-1:50, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))
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别名
- KISS1
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背景
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Description: Metastasis suppressor protein in malignant melanomas and in some breast cancers. May regulate events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. Generates a C-terminally amidated peptide, metastin which functions as the endogenous ligand of the G-protein coupled receptor GPR54. Activation of the receptor inhibits cell proliferation and cell migration, key characteristics of tumor metastasis. Kp-10 is a decapeptide derived from the primary translation product, isolated in conditioned medium of first trimester trophoblast. Kp-10, but not other kisspeptins, increased intracellular Ca2+ levels in isolated first trimester trophoblasts. Kp-10 is a paracrine/endocrine regulator in fine-tuning trophoblast invasion generated by the trophoblast itself. The receptor is also essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/GPR54 system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood.
Gene: KISS1
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分子量
- 15kDa
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基因ID
- 3814
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UniProt
- Q15726
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途径
- Positive Regulation of Peptide Hormone Secretion
抗原
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