GLRA1 抗体 (Internal Region)
-
- 抗原 See all GLRA1 抗体
- GLRA1 (Glycine Receptor, alpha 1 (GLRA1))
-
抗原表位
- Internal Region
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This GLRA1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 特异性
- GLRA1 Antibody detects endogenous levels of total GLRA1.
- 预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human GLRA1, corresponding to a region within the internal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product GLRA1 Primary Antibody
-
anti-Glycine Receptor, alpha 1 (GLRA1) (AA 23-113) antibody
GLRA1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glycine Receptor, alpha 1 (GLRA1) (AA 121-220) antibodyGLRA1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E6 unconjugated
anti-Glycine Receptor, alpha 1 (GLRA1) (AA 29-247) antibodyGLRA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Glycine Receptor, alpha 1 (GLRA1) (AA 29-154) antibodyGLRA1 适用: 人 WB, ELISA, IHC, ICC, FACS, Neut 宿主: 小鼠 Monoclonal 7F8E2 unconjugated
anti-Glycine Receptor, alpha 1 (GLRA1) antibodyGLRA1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Glycine Receptor, alpha 1 (GLRA1) (AA 121-220) antibodyGLRA1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4D9 unconjugated
anti-Glycine Receptor, alpha 1 (GLRA1) (N-Term) antibodyGLRA1 适用: 人, 小鼠, 大鼠 WB, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Glycine Receptor, alpha 1 (GLRA1) (Internal Region) antibodyVerified GLRA1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Glycine Receptor, alpha 1 (GLRA1) antibodyGLRA1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glycine Receptor, alpha 1 (GLRA1) (AA 1-449) antibodyGLRA1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- WB 1:500-1:2000, IHC 1:50-1:100, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
-
- 抗原
- GLRA1 (Glycine Receptor, alpha 1 (GLRA1))
- 别名
- GLRA1 (GLRA1 产品)
- 别名
- GLYRA1 antibody, HKPX1 antibody, STHE antibody, [a]Z1 antibody, B230397M16Rik antibody, nmf11 antibody, oscillator antibody, ot antibody, spasmodic antibody, spd antibody, glycine receptor alpha 1 antibody, glycine receptor, alpha 1 antibody, glycine receptor, alpha 1 subunit antibody, GLRA1 antibody, Glra1 antibody, glra1 antibody
- 背景
-
Description: Glycine receptors are ligand-gated chloride channels (PubMed:23994010, PubMed:25730860). Channel opening is triggered by extracellular glycine (PubMed:2155780, PubMed:7920629, PubMed:14551753, PubMed:16144831, PubMed:22715885, PubMed:22973015, PubMed:25973519, PubMed:9009272). Channel opening is also triggered by taurine and beta-alanine (PubMed:16144831, PubMed:9009272). Channel characteristics depend on the subunit composition, heteropentameric channels are activated by lower glycine levels and display faster desensitization (PubMed:14551753). Plays an important role in the down-regulation of neuronal excitability (PubMed:8298642, PubMed:9009272). Contributes to the generation of inhibitory postsynaptic currents (PubMed:25445488). Channel activity is potentiated by ethanol (PubMed:25973519). Potentiation of channel activity by intoxicating levels of ethanol contribute to the sedative effects of ethanol (By similarity).
Gene: GLRA1
- 分子量
- 53kDa
- 基因ID
- 2741
- UniProt
- P23415
- 途径
- Synaptic Membrane
-
