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XRN2 抗体

This anti-XRN2 antibody is a 兔 多克隆 antibody detecting XRN2 in WB, ELISA, IHC, ICC 和 IF. Suitable for 人, 小鼠 和 猴.
产品编号 ABIN6266072
发货至: 中国

Quick Overview for XRN2 抗体 (ABIN6266072)

抗原

See all XRN2 抗体
XRN2 (5'-3' Exoribonuclease 2 (XRN2))

适用

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人, 小鼠, 猴

宿主

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克隆类型

  • 20
  • 9
多克隆

标记

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This XRN2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)
  • 特异性

    XRN2 Antibody detects endogenous levels of XRN2

    交叉反应

    人, 猴, 小鼠

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human XRN2

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C.Stable for 12 months from date of receipt

    有效期

    12 months
  • 抗原

    XRN2 (5'-3' Exoribonuclease 2 (XRN2))

    别名

    XRN2

    背景

    Description: Possesses 5'->3' exoribonuclease activity (By similarity). May promote the termination of transcription by RNA polymerase II. During transcription termination, cleavage at the polyadenylation site liberates a 5' fragment which is subsequently processed to form the mature mRNA and a 3' fragment which remains attached to the elongating polymerase. The processive degradation of this 3' fragment by this protein may promote termination of transcription. Binds to RNA polymerase II (RNAp II) transcription termination R-loops formed by G-rich pause sites (PubMed:21700224).

    Gene: XRN2

    分子量

    108kDa

    基因ID

    22803

    UniProt

    Q9H0D6
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