XRN2 抗体
Quick Overview for XRN2 抗体 (ABIN6266072)
抗原
See all XRN2 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- XRN2 Antibody detects endogenous levels of XRN2
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交叉反应
- 人, 猴, 小鼠
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human XRN2
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亚型
- IgG
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anti-5'-3' Exoribonuclease 2 (XRN2) (AA 398-547) antibody
XRN2 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 9F7G11 unconjugated
anti-5'-3' Exoribonuclease 2 (XRN2) (AA 81-130) antibodyXRN2 适用: 人, 小鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-5'-3' Exoribonuclease 2 (XRN2) (N-Term) antibodyXRN2 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-5'-3' Exoribonuclease 2 (XRN2) (N-Term) antibodyXRN2 适用: 人, 小鼠, 猴 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-5'-3' Exoribonuclease 2 (XRN2) (AA 48-76) antibodyXRN2 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000 IHC 1:50-1:200, IF/ICC 1:100-1:500
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
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有效期
- 12 months
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- XRN2 (5'-3' Exoribonuclease 2 (XRN2))
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别名
- XRN2
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背景
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Description: Possesses 5'->3' exoribonuclease activity (By similarity). May promote the termination of transcription by RNA polymerase II. During transcription termination, cleavage at the polyadenylation site liberates a 5' fragment which is subsequently processed to form the mature mRNA and a 3' fragment which remains attached to the elongating polymerase. The processive degradation of this 3' fragment by this protein may promote termination of transcription. Binds to RNA polymerase II (RNAp II) transcription termination R-loops formed by G-rich pause sites (PubMed:21700224).
Gene: XRN2
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分子量
- 108kDa
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基因ID
- 22803
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UniProt
- Q9H0D6
抗原
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