VPS11 抗体 (Internal Region)
Quick Overview for VPS11 抗体 (Internal Region) (ABIN6265995)
抗原
See all VPS11 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- VPS11 Antibody detects endogenous levels of total VPS11.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human VPS11, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Vacuolar Protein Sorting 11 Homolog (VPS11) antibody
VPS11 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Vacuolar Protein Sorting 11 Homolog (VPS11) (Center) antibodyVPS11 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting 11 Homolog (VPS11) (Internal Region) antibodyVerified VPS11 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Vacuolar Protein Sorting 11 Homolog (VPS11) (AA 842-941) antibodyVPS11 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1H1 unconjugated
anti-Vacuolar Protein Sorting 11 Homolog (VPS11) (AA 692-941) antibodyVPS11 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting 11 Homolog (VPS11) (AA 842-941) antibodyVPS11 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- VPS11 (Vacuolar Protein Sorting 11 Homolog (VPS11))
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别名
- VPS11
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背景
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Description: Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes which are proposed to be involved in the Rab5-to-Rab7 endosome conversion probably implicating MON1A/B, and via binding SNAREs and SNARE complexes to mediate tethering and docking events during SNARE-mediated membrane fusion. The HOPS complex is proposed to be recruited to Rab7 on the late endosomal membrane and to regulate late endocytic, phagocytic and autophagic traffic towards lysosomes. The CORVET complex is proposed to function as a Rab5 effector to mediate early endosome fusion probably in specific endosome subpopulations (PubMed:11382755, PubMed:23351085, PubMed:24554770, PubMed:25266290, PubMed:25783203). Required for fusion of endosomes and autophagosomes with lysosomes (PubMed:25783203). Involved in cargo transport from early to late endosomes and required for the transition from early to late endosomes (PubMed:21148287). Involved in the retrograde Shiga toxin transport (PubMed:23593995).
Gene: VPS11
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分子量
- 108-112 kDa
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基因ID
- 55823
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UniProt
- Q9H270
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途径
- SARS-CoV-2 Protein Interactome
抗原
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