USP34 抗体 (N-Term)
Quick Overview for USP34 抗体 (N-Term) (ABIN6265924)
抗原
See all USP34 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- USP34 Antibody detects endogenous levels of total USP34.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human USP34, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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anti-Ubiquitin Specific Peptidase 34 (USP34) antibody
USP34 适用: 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 34 (USP34) (AA 3296-3395) antibodyUSP34 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2E2 unconjugated
anti-Ubiquitin Specific Peptidase 34 (USP34) (AA 3296-3395) antibodyUSP34 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- USP34 (Ubiquitin Specific Peptidase 34 (USP34))
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别名
- USP34
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背景
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Description: Ubiquitin hydrolase that can remove conjugated ubiquitin from AXIN1 and AXIN2, thereby acting as a regulator of Wnt signaling pathway. Acts as an activator of the Wnt signaling pathway downstream of the beta-catenin destruction complex by deubiquitinating and stabilizing AXIN1 and AXIN2, leading to promote nuclear accumulation of AXIN1 and AXIN2 and positively regulate beta-catenin (CTNBB1)-mediated transcription. Recognizes and hydrolyzes the peptide bond at the C-terminal Gly of ubiquitin. Involved in the processing of poly-ubiquitin precursors as well as that of ubiquitinated proteins.
Gene: USP34
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分子量
- 404 kDa
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基因ID
- 9736
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UniProt
- Q70CQ2
抗原
-
