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UBE2D1 抗体 (C-Term)

This 兔 多克隆 anti-UBE2D1 antibody specifically detects UBE2D1 in WB, IHC, ELISA, IF 和 ICC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN6265844
发货至: 中国
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Quick Overview for UBE2D1 抗体 (C-Term) (ABIN6265844)

抗原

See all UBE2D1 抗体
UBE2D1 (Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

  • 43
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多克隆

标记

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This UBE2D1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

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    C-Term

    特异性

    UBE2D1 Antibody detects endogenous levels of total UBE2D1.

    预测反应

    Pig,Bovine,Horse,Sheep,Dog,Chicken,Xenopus

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human UBE2D1, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    UBE2D1 (Ubiquitin-Conjugating Enzyme E2D 1 (UBE2D1))

    别名

    UBE2D1

    背景

    Description: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins (PubMed:22496338). In vitro catalyzes 'Lys-48'-linked polyubiquitination (PubMed:20061386). Mediates the selective degradation of short-lived and abnormal proteins. Functions in the E6/E6-AP-induced ubiquitination of p53/TP53. Mediates ubiquitination of PEX5 and auto-ubiquitination of STUB1, TRAF6 and TRIM63/MURF1 (PubMed:18042044, PubMed:18359941). Ubiquitinates STUB1-associated HSP90AB1 in vitro (PubMed:18042044). Lacks inherent specificity for any particular lysine residue of ubiquitin (PubMed:18042044). Essential for viral activation of IRF3 (PubMed:19854139). Mediates polyubiquitination of CYP3A4 (PubMed:19103148).

    Gene: UBE2D1

    分子量

    17kDa

    基因ID

    7321

    UniProt

    P51668

    途径

    Activation of Innate immune Response, Toll-Like Receptors Cascades
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