THOC1 抗体 (C-Term)
Quick Overview for THOC1 抗体 (C-Term) (ABIN6265557)
抗原
See all THOC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- THOC1 Antibody detects endogenous levels of total THOC1.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human THOC1, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-THO Complex 1 (THOC1) antibody
THOC1 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-THO Complex 1 (THOC1) (AA 428-657) antibodyTHOC1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-THO Complex 1 (THOC1) (C-Term) antibodyKO Validated THOC1 适用: 人 WB, IF, IP, IHC (p), ICC, ChIP 宿主: 兔 Polyclonal unconjugated
anti-THO Complex 1 (THOC1) (C-Term) antibodyTHOC1 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, 豚鼠, Cow, 斑马鱼, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-THO Complex 1 (THOC1) (AA 428-657) antibodyTHOC1 适用: 人 WB, IHC, ELISA, ChIP 宿主: 兔 Polyclonal unconjugated
anti-THO Complex 1 (THOC1) (AA 511-560) antibodyTHOC1 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, 豚鼠, Cow, 猴, 小鸡 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-THO Complex 1 (THOC1) (C-Term) antibodyTHOC1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-THO Complex 1 (THOC1) (AA 540-570), (C-Term) antibodyTHOC1 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
anti-THO Complex 1 (THOC1) (AA 541-570), (C-Term) antibodyTHOC1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- THOC1 (THO Complex 1 (THOC1))
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别名
- THOC1
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背景
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Description: Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. Regulates transcriptional elongation of a subset of genes. Involved in genome stability by preventing co-transcriptional R-loop formation.
Gene: THOC1
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分子量
- 76 kDa
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基因ID
- 9984
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UniProt
- Q96FV9
抗原
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