SYNPO2 抗体 (Internal Region)
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Quick Overview for SYNPO2 抗体 (Internal Region) (ABIN6265395)
抗原
See all SYNPO2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- Synaptopodin Antibody detects endogenous levels of total Synaptopodin.
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预测反应
- Bovine,Horse
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human Synaptopodin, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Synaptopodin 2 (SYNPO2) (C-Term) antibody
SYNPO2 适用: 人, 小鼠, 大鼠, 豚鼠, 马, Cow, 犬, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Synaptopodin 2 (SYNPO2) (N-Term) antibodySYNPO2 适用: 人, 小鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- SYNPO2 (Synaptopodin 2 (SYNPO2))
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别名
- SYNPO2
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背景
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Description: Has an actin-binding and actin-bundling activity. Can induce the formation of F-actin networks in an isoform-specific manner (PubMed:24005909, PubMed:23225103). At the sarcomeric Z lines is proposed to act as adapter protein that links nascent myofibers to the sarcolemma via ZYX and may play a role in early assembly and stabilization of the Z lines. Involved in autophagosome formation. May play a role in chaperone-assisted selective autophagy (CASA) involved in Z lines maintenance in striated muscle under mechanical tension, may link the client-processing CASA chaperone machinery to a membrane-tethering and fusion complex providing autophagosome membranes (By similarity). Involved in regulation of cell migration (PubMed:22915763, PubMed:25883213). May be a tumor suppressor (PubMed:16885336).
Gene: SYNPO2
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分子量
- 99-115 kDa
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基因ID
- 171024
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UniProt
- Q9UMS6
抗原
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