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- 抗原 See all SYNPO2 抗体
- SYNPO2 (Synaptopodin 2 (SYNPO2))
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抗原表位
- N-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SYNPO2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects SYNPO2 at N-term.
- 交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- 20 amino acid peptide near the amino terminus of human SYNPO2
- Top Product
- Discover our top product SYNPO2 Primary Antibody
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anti-Synaptopodin 2 (SYNPO2) (Internal Region) antibody
SYNPO2 适用: 人, 小鼠, 大鼠 IHC, WB 宿主: 兔 Polyclonal unconjugated
anti-Synaptopodin 2 (SYNPO2) (C-Term) antibodySYNPO2 适用: 人, 小鼠, 大鼠, 马, 豚鼠, 兔, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- 抗原
- SYNPO2 (Synaptopodin 2 (SYNPO2))
- 别名
- SYNPO2 (SYNPO2 产品)
- 别名
- SYNOP2 antibody, RGD1564779 antibody, 1110069I04Rik antibody, 2310068J10Rik antibody, 9530006G20Rik antibody, AI848603 antibody, Myo antibody, synaptopodin 2 antibody, synaptopodin-2 antibody, SYNPO2 antibody, LOC100484043 antibody, Synpo2 antibody
- 背景
- SYNPO2 was initially identified as myopodin, a member of the synaptopodin family that contains one PPXY motif and multiple PXXP motifs. It colocalizes with alpha-actinin and is found at the Z-disc and during stress conditions will translocate to the nucleus, suggesting that it is part of signaling pathways in addition to its function as a structural protein. SYNPO2 has been shown to bind to calmodulin, alpha-actinin, and smooth muscle myosin and will stimulate actin polymerization in a calmodulin dependent manner, consistent with its proposed role in organizing the cytoskeleton. While deletion of SYNPO2 has been reported to be highly correlated with the invasiveness of prostate cancers, other reports suggest that down-regulation of SYNPO2 reduces the invasiveness and motility of prostate cancer cells.
- 基因ID
- 171024
- NCBI登录号
- NP_001122405
- UniProt
- Q9UMS6
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