SENP1 抗体 (N-Term)
Quick Overview for SENP1 抗体 (N-Term) (ABIN6264983)
抗原
See all SENP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- SENP1 Antibody detects endogenous levels of total SENP1.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human SENP1, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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anti-SUMO1/sentrin Specific Peptidase 1 (SENP1) (AA 220-420) antibody
SENP1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SUMO1/sentrin Specific Peptidase 1 (SENP1) (AA 63-214) antibodySENP1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SUMO1/sentrin Specific Peptidase 1 (SENP1) antibodySENP1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SUMO1/sentrin Specific Peptidase 1 (SENP1) (AA 28-59), (N-Term) antibodySENP1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB0647 unconjugated
anti-SUMO1/sentrin Specific Peptidase 1 (SENP1) (AA 28-59) antibodySENP1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-SUMO1/sentrin Specific Peptidase 1 (SENP1) (C-Term) antibodySENP1 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, Pig, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-SUMO1/sentrin Specific Peptidase 1 (SENP1) (AA 221-460) antibodySENP1 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 1D7 unconjugated
anti-SUMO1/sentrin Specific Peptidase 1 (SENP1) (N-Term) antibodySENP1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SUMO1/sentrin Specific Peptidase 1 (SENP1) (AA 578-590) antibodySENP1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-SUMO1/sentrin Specific Peptidase 1 (SENP1) (N-Term) antibodySENP1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- SENP1 (SUMO1/sentrin Specific Peptidase 1 (SENP1))
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别名
- SENP1
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背景
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Description: Protease that catalyzes two essential functions in the SUMO pathway. The first is the hydrolysis of an alpha-linked peptide bond at the C-terminal end of the small ubiquitin-like modifier (SUMO) propeptides, SUMO1, SUMO2 and SUMO3 leading to the mature form of the proteins. The second is the deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins, by cleaving an epsilon-linked peptide bond between the C-terminal glycine of the mature SUMO and the lysine epsilon-amino group of the target protein. Deconjugates SUMO1 from HIPK2 (PubMed:16253240). Deconjugates SUMO1 from HDAC1 and BHLHE40/DEC1, which decreases its transcriptional repression activity (PubMed:21829689). Deconjugates SUMO1 from CLOCK, which decreases its transcriptional activation activity (PubMed:23160374). Deconjugates SUMO2 from MTA1 (PubMed:21965678). Desumoylates CCAR2 which decreases its interaction with SIRT1 (PubMed:25406032). Deconjugates SUMO1 from GPS2 (PubMed:24943844).
Gene: SENP1
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分子量
- 73kDa
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基因ID
- 29843
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UniProt
- Q9P0U3
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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