RNLS 抗体 (C-Term)
Quick Overview for RNLS 抗体 (C-Term) (ABIN6264793)
抗原
See all RNLS 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- RNLS Antibody detects endogenous levels of total RNLS.
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预测反应
- Pig,Horse,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human RNLS, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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应用备注
- WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- RNLS (Renalase, FAD-Dependent Amine Oxidase (RNLS))
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别名
- RNLS
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背景
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Description: Catalyzes the oxidation of the less abundant 1,2-dihydro-beta-NAD(P) and 1,6-dihydro-beta-NAD(P) to form beta-NAD(P)+. The enzyme hormone is secreted by the kidney, and circulates in blood and modulates cardiac function and systemic blood pressure. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis.
Gene: RNLS
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分子量
- 38 kDa
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基因ID
- 55328
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UniProt
- Q5VYX0
抗原
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