RANBP1 抗体 (N-Term)
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北京 101111
Quick Overview for RANBP1 抗体 (N-Term) (ABIN6264631)
抗原
See all RANBP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- RanBP1 Antibody detects endogenous levels of total RanBP1.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human RanBP1, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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anti-RAN Binding Protein 1 (RANBP1) (C-Term) antibody
Verified RANBP1 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-RAN Binding Protein 1 (RANBP1) antibodyKO Validated RANBP1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-RAN Binding Protein 1 (RANBP1) (AA 2-201) antibodyRANBP1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-RAN Binding Protein 1 (RANBP1) (AA 52-111) antibodyRANBP1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-RAN Binding Protein 1 (RANBP1) (AA 1-187), (N-Term) antibodyRANBP1 适用: 人, 小鼠, 大鼠, Cow WB, IF 宿主: 兔 Polyclonal unconjugated
anti-RAN Binding Protein 1 (RANBP1) (AA 86-116) antibodyRANBP1 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-RAN Binding Protein 1 (RANBP1) (AA 1-100) antibodyRANBP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-RAN Binding Protein 1 (RANBP1) (C-Term) antibodyRANBP1 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-RAN Binding Protein 1 (RANBP1) (AA 1-201) antibodyRANBP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-RAN Binding Protein 1 (RANBP1) (C-Term) antibodyRANBP1 适用: 人, Cow, 马, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- RANBP1 (RAN Binding Protein 1 (RANBP1))
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别名
- RANBP1
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背景
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Description: Plays a role in RAN-dependent nucleocytoplasmic transport. Alleviates the TNPO1-dependent inhibition of RAN GTPase activity and mediates the dissociation of RAN from proteins involved in transport into the nucleus (By similarity). Induces a conformation change in the complex formed by XPO1 and RAN that triggers the release of the nuclear export signal of cargo proteins (PubMed:20485264). Promotes the disassembly of the complex formed by RAN and importin beta. Promotes dissociation of RAN from a complex with KPNA2 and CSE1L (By similarity). Required for normal mitotic spindle assembly and normal progress through mitosis via its effect on RAN (PubMed:17671426). Does not increase the RAN GTPase activity by itself, but increases GTP hydrolysis mediated by RANGAP1 (PubMed:7882974). Inhibits RCC1-dependent exchange of RAN-bound GDP by GTP (PubMed:7882974, PubMed:7616957).
Gene: RANBP1
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分子量
- 23 kDa
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基因ID
- 5902
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UniProt
- P43487
抗原
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