RAB43 抗体 (Internal Region)
Quick Overview for RAB43 抗体 (Internal Region) (ABIN6264583)
抗原
See all RAB43 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- RAB43 Antibody detects endogenous levels of total RAB43.
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预测反应
- Pig,Horse
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human RAB43, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-RAB43, Member RAS Oncogene Family (RAB43) (AA 113-210) antibody
RAB43 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 5G4 unconjugated
anti-RAB43, Member RAS Oncogene Family (RAB43) (AA 1-212) antibodyRAB43 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-RAB43, Member RAS Oncogene Family (RAB43) (AA 1-212) antibodyRAB43 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- RAB43 (RAB43, Member RAS Oncogene Family (RAB43))
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别名
- RAB43
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背景
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Description: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. The low intrinsic GTPase activity of RAB43 is activated by USP6NL. Involved in retrograde transport from the endocytic pathway to the Golgi apparatus. Involved in the transport of Shiga toxin from early and recycling endosomes to the trans-Golgi network. Required for the structural integrity of the Golgi complex. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis.
Gene: RAB43
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分子量
- 23 kDa
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基因ID
- 339122
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UniProt
- Q86YS6
抗原
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